Answers

Be sure you know the biochemical composition of the cytoplasmic granules of neutrophils (polymorphonuclear leukocytes), eosinophils, and basophils.

Questions

1. What is the functional significance of the cytoplasmic staining affinities of the basophilic erythroblast, polychromatophilic erythroblast, normoblast and erythrocyte?
   Basophilic erythroblast - ribosomes predominate for production of hemoglobin and transferrin receptors.
   Polychromatophilic erythroblast - hemoglobin synthesis beginning.
   Normoblast - hemoglobin fills cytoplasm, pyknotic nucleus.
   Erythrocyte - anuclear cell, hemoglobin fills cytoplasm.
2. Is the nucleus more intensely basophilic in an erythroblast or a normoblast? Normoblast What is the significance of these nuclear changes? Erythroblasts are cells in which DNA is transcribed; the chromatin is no longer active in the normoblast.
3. What is the origin of platelets? Megakaryocyte